Whether you’re in pharmaceuticals, electronics, biotechnology, or advanced manufacturing, building a cleanroom is a major investment. The right planning and knowledge will help you avoid costly mistakes, ensure compliance with ISO 14644 standards, and achieve the level of cleanliness your operations require.
This guide walks you through the essentials of cleanroom construction — from defining requirements to certification — so you can approach your project with confidence.
1. Define Your Cleanroom Requirements
Before contacting vendors, get clarity on your needs:
- Application – What processes will the cleanroom support?
- Cleanliness Level – Which ISO class is required?
- Space – How much area is available for installation?
- Special Requirements – Do you need humidity or temperature control, chemical resistance, biosafety features, or ESD protection?
💡 Tip: Not sure which ISO class you need? A qualified cleanroom provider can advise based on your industry and application.
2. Key Questions to Ask Cleanroom Vendors
When evaluating builders or suppliers, ask:
- Do you have experience in my industry?
- Can you meet ISO 14644-1 certification standards?
- Will you manage design, permits, installation, testing, and certification?
- Do you provide post-build maintenance and support?
A reliable provider will also present material specifications, airflow strategies, and equipment details upfront.
3. Core Features of a High-Quality Cleanroom
Ensure the design includes:
- HEPA/ULPA filtration aligned with your ISO class
- Positive/negative pressure controls for contamination management
- Gowning rooms and airlocks to reduce contamination risk
- Pass-through chambers for material transfer
- Cleanroom-rated walls, ceilings, flooring, and furniture
- Integrated HVAC, lighting, and utilities
All elements should support low particle shedding, easy cleaning, and long-term durability.
4. Testing and Certification
Before use, a cleanroom must be certified through:
- Particle count testing
- Airflow visualization (smoke tests)
- Filter integrity checks
- Air change rate and pressure differential verification
Confirm your provider issues a final certification report and offers annual recertification services.
5. Additional Considerations
Depending on your industry, you may also need:
- ESD-safe materials for electronics
- Precision humidity and temperature control for sensitive processes
- Fire suppression and safety systems
- Custom furniture and equipment integration
Start Your Cleanroom Project with Confidence
Building a cleanroom is a critical investment in product quality, compliance, and safety. With the right planning and expert guidance, you can ensure your facility meets the highest standards.
📞 Need expert advice on cleanroom design, construction, or certification? Contact our team today to discuss your project.