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Frequently Asked Questions
Get clarity on the details — from design and materials to timelines and maintenance.
The highest grade of cleanroom is ISO Class 1, which allows the fewest particles per cubic meter of air. In pharmaceutical terms, the strictest level is Grade A, used for critical operations like sterile filling. These environments require advanced filtration, strict controls, and specialized protocols to maintain ultra-clean conditions.
Cleanroom classifications define how many particles are allowed in the air.
The two most common systems are:
ISO 14644-1 (International Standard): Ranges from ISO Class 1 (the cleanest, near particle-free) to ISO Class 9 (least strict). Each class specifies the maximum number of particles of a certain size per cubic meter of air.
EU GMP / FDA Grades (Pharma): Uses Grades A to D, with Grade A being the most sterile, typically for aseptic filling, and Grade D for less critical operations.
ISO 14644-1 defines cleanroom classes by the number of particles allowed per cubic meter of air. The lower the class number, the cleaner the air.
| ISO Class | Maximum Particles (≥0.5 μm per m³) | Typical Application |
|---|---|---|
| ISO 1 | 10 | Advanced nanotech, microelectronics |
| ISO 2 | 100 | Ultra-sensitive processes |
| ISO 3 | 1,000 | Aerospace, biotech R&D |
| ISO 4 | 10,000 | Semiconductor manufacturing |
| ISO 5 | 100,000 | Aseptic filling, pharmaceutical production |
| ISO 6 | 1,000,000 | Medical device assembly |
| ISO 7 | 352,000,000 | Pharmaceutical prep areas |
| ISO 8 | 3,520,000,000 | General clean manufacturing |
| ISO 9 | 35,200,000,000 | Controlled but less strict areas |
We supply ESD flooring, epoxy systems, vinyl, and raised floor panels—all durable, chemical-resistant, seamless, and designed for sterile, high-traffic environments.
Nupon cleanrooms support pharmaceuticals, biotechnology, electronics, semiconductors, automotive, food & beverage, chemical processing, healthcare, aerospace, and research laboratories.